Cardiovascular physiology. Simpler.
VIRTUheart is a software package that models cardiovascular physiology from medical imaging. It is an academic development project led by the Mathematical Modelling in Medicine Research Group, based at the University of Sheffield, UK. The VIRTUheart team include interventional cardiologists, engineers, mathematicians and software developers.
Originally conceived in 2012, it has been developed over the last ten years and now has extended applications and uses. The aim of VIRTUheart is to generate clinically useful data to help support clinical decisions when treating patients in the cardiac catheter laboratory.
virtual FFR (aka vFFR) computes fractional flow reserve (FFR), without a pressure wire, using computational fluid dynamics (CFD), based on a 3D reconstruction of the arterial anatomy. VIRTUheart was the original vFFR model derived from invasive angiography, first published in 2013. Back then it took >24 hours to compute, but now takes just seconds. It is also capable of virtual stenting [ref] and virtual pressure pull-back.
virtuQ computes absolute coronary blood flow (in mL/min), absolute microvascular resistance, coronary flow reserve and stenosis resistance. It also calculates the reduction in flow due to coronary artery disease. virtuQ computes these parameters from data generated during a standard angiogram and pressure wire study. No additional hardware or drug infusion is required. Latest publication.
For patients and public
VIRTUheart is a medical research and development project run by a team of specialist heart doctors, engineers and software developers in Sheffield, UK. The project has been running for over a decade. Our aim is to construct computer-based models, based on patient tests, to simulate important changes in blood pressure and flow, inside the heart and the coronary arteries, that can be used to make better decisions about how to treat people with heart disease.
We are grateful to the Cardiovascular Patient Panel at Sheffield Teaching Hospitals NHS Trust who have, provided input, guidance and advice regarding our research and development.
Images from VIRTUheart work
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We are grateful to those who have supported aspects of the project and our team over the years.
Collaborators and affiliations
We have enjoyed working alongside some wonderful people and institutions.